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The researchers, attracted by characteristics of longevity of the Sardinian people, analize the genetic patrimony of the inhabitants of four different municipalities in Ogliastra: Arzana, Elini, Ilbono and Lanusei. The choice to focus the project "ProgeNIA" on Ogliastra is because of the characteristics innate in the peaple of these places, such as the proclivity of staying alive for so long, the stability of the environment and the geographical isolation. For all these reasons Ogliastra is a natural laboratory for the study of longevity.